'Forever Chemicals' Exposures May Compound Diabetes Risk
Women in midlife exposed to combinations of perfluoroalkyl and polyfluoroalkyl substances (PFASs), dubbed "forever and everywhere chemicals", are at increased risk of developing diabetes, similar to the magnitude of risk associated with overweight, and even greater than the risk associated with smoking. Sources of PFAS exposure can run the gamut from nonstick cookware, food wrappers, and waterproof fabrics to cosmetics and even drinking water.

A prospective study of 1237 women, with a median age of 49.4 years, who were diabetes-free upon entering the Study of Women's Health Across the Nation – Multi-Pollutant Study (SWAN-MPS) between 1999 and 2000 and followed until 2017. Blood samples taken throughout the study were analyzed for serum concentrations of seven PFASs.

Over the study period, there were 102 cases of incident diabetes, representing a rate of 6 cases per 1000 person-years. Type of diabetes was not determined, but given the age of study participants, most were assumed to have type 2 diabetes. The findings suggest that PFAS may be an important risk factor for diabetes that has a substantial public health impact.

Source: https://www.medscape.com/viewarticle/971982?src=rss#vp_2