1)Clinical details- patient complained of reduced mouth opening
2)Provisional daignosis- Oral submucous fibrosis / oral squamous cell carcinoma
3)Microscopic findings - Three soft tissues bits received. All are brownish black in colour, soft to firm in consistency.
4) Microscopic findings- H&E stained sections show parakeratinized stratified squamous epithelium. The underlying connective tissue exhibits infiltrated epithelial cells in the form of sheets, islands and cords. These cells exhibit dysplastic features like altered nucleo-cytoplasmic ratio, nuclear hyperchromatism, epithelial pearls, abnormal mitotic figures etc. The intermediate connective tissue exhibits mild to moderate inflammatory cell infiltration consisting predominantly of lymphocytes and plasma cells. There are blood vessels also noted.
5) Histopathological diagnosis : Histopathological picture is suggestive of WELL DIFFERENTIATED ORAL SQUAMOUS CELL CARCINOMA