1st confirmed case of baby infected with COVID-19 in the wom
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Doctors in France have described what they said was the first confirmed case of a newborn infected in the womb with COVID-19 by the mother.

The baby boy, born in March, suffered brain swelling and neurological symptoms linked to COVID-19 in adults, but has since recovered, they reported Tuesday in the journal Nature Communications. "We have shown that the transmission from the mother to the foetus across the placenta is possible during the last weeks of pregnancy," doctor said.

The transmission is confirmed by comprehensive virological and pathological investigations. In detail, SARS-CoV-2 causes: (1) maternal viremia, (2) placental infection demonstrated by immunohistochemistry and very high viral load; placental inflammation, as shown by histological examination and immunohistochemistry, and (3) neonatal viremia following placental infection.

The baby began to develop severe symptoms 24 hours after birth, including severe rigidity of the body, damage to white matter in the brain, and extreme irritability.

But before doctors could settle on a course of treatment, the symptoms began to recede. Within three weeks, the newborn had almost fully recovered on his own. Three months later, his mother is without symptoms.

Among the thousands of babies born to mothers with COVID-19, no more than one or two percent have tested positive for the virus, and even fewer show serious symptoms.

"The most important message for pregnant women remains to avoid infection through paying attention to hand washing and social distancing measures," she said.

Source: https://www.nature.com/articles/s41467-020-17436-6
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