2-3 cups of coffee a day may reduce kidney injury risk by 23
In the Atherosclerosis Risk in Communities (ARIC) Study, a prospective cohort study of 14,207 adults aged 45 to 64 years, coffee consumption (cups/d) was assessed at a single visit via food frequency questionnaires and compared with incident AKI defined by hospitalization with an AKI-related International Classification of Diseases code. In ARIC, there were 1694 cases of incident AKI in a median of 24 follow-up years. Higher coffee consumption was associated with lower AKI risk versus no consumption. Less than 1 cup/d: 0.92; 1 cup/d: 1.08; 2 to 3 cups/d: 0.83; more than 3 cups/d: 0.83. Trends for AKI risk across coffee categories remained significant after multivariable adjustment for age, sex, race-center, education, total daily energy intake, physical activity, smoking, alcohol intake, diet quality (Dietary Approaches to Stop Hypertension [DASH] score), systolic blood pressure (BP), diabetes status, use of antihypertensive agents, estimated glomerular filtration rate (eGFR), and body mass index (BMI). Higher coffee intake was associated with a lower risk of incident AKI and could present an opportunity for cardiorenal protection through diet.

Source: https://www.kireports.org/article/S2468-0249(22)01369-9/fulltext