3D heart printing breakthrough
US scientists announced they have successfully built functional heart parts out of collagen with a 3D bioprinter, using a breakthrough technique they say could one day create entire organs.

Their method, which was described in the journal Science, replicates the body’s own complex biological scaffolds using its most abundant protein at the highest level of precision yet achieved. The technique, known as Freeform Reversible Embedding of Suspended Hydrogels (FRESH), has allowed the researchers to overcome many challenges associated with existing 3D bioprinting methods, and to achieve unprecedented resolution and fidelity using soft and living materials.

The team used MRI scans of human hearts to reproduce patient-specific parts, which achieved outcomes like synchronised beating and opening and closing of valves.

In April, an Israeli team unveiled a 3D print of a heart with human tissue and vessels, but the organ did not have the ability to pump. Previous attempts at printing the scaffolds, known as extracellular matrices, had been hindered by limitations that resulted in poor tissue fidelity and low resolutions.

“What we were able to show was you can actually 3D print a heart valve out of collagen,” Adam Feinberg, a co-author of the paper who is a professor of biomedical engineering at Carnegie Mellon University, told AFP. Looking forward, FRESH has applications in many aspects of regenerative medicine, from wound repair to organ bioengineering, but it is just one piece of a growing biofabrication field. "Really what we're talking about is the convergence of technologies," says Feinberg. "Not just what my lab does in bioprinting, but also from other labs and small companies in the areas of stem cell science, machine learning, and computer simulation, as well as new 3D bioprinting hardware and software."

Also read: https://www.plexusmd.com/md/post/-majorbreakthrough-world's-first-3d-printed-heart/45548

Source: https://www.thejakartapost.com/life/2019/08/02/us-scientists-announce-3d-heart-printing-breakthrough.html
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Dr. T●●●●z H●●●●●●i
Dr. T●●●●z H●●●●●●i Oral and Maxillofacial Surgery
Great work!! More milestones to be achieved!!
Aug 10, 2019Like