A Case of Kawasaki Disease with Coronary Aneurysm Responding
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Kawasaki disease (KD) is an acute febrile, systemic vasculitic syndrome of unknown etiology, occurring primarily in children younger than 5 years of age. Administration of IVIG within the first 10 days after onset of fever in combination with high dose aspirin reduces the risk of coronary artery damage in KD. IVIG treatment ?10 days after illness onset was found to be insufficient for preventing coronary artery lesions.IVIG should be administered to children presenting after the 10th day of illness if they have either persistent fever or aneurysms and ongoing systemic inflammation, as manifested by elevated erythrocyte sedimentation rate, C-reactive protein. However, the relative role of repeated doses of IVIG in refractory KD is still unknown. We report the case of refractory KD with coronary aneurysm responding the 4th IVIG treatment.......

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137746/
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