A Case of Malignant Melanoma of the Uterine Cervix with Diss
Case Presentation
A 66-year-old woman presented with postmenopausal bleeding.Gynecologic examination and colposcopic findingsrevealed a 2 cm polypoid blackish-pigmented tumor in the cervix, and multiple small blackish-pigmented lesions were found throughout the vaginal wall, spreading to the lower third of the vagina (Figure 1). Cervical Pap smear showed
MM. MRI and PET/CT did not detect any distant or lymph
node metastases. The serum level of 5-SCD, a tumor marker
for melanoma, was 5.1 nmol/L (normal level: 1.5?8.0). She
underwent radical hysterectomy, bilateral salpingooophorectomy, pelvic lymphadenectomy, and total vaginectomy without any major complications, and optimal surgery was achieved with no residual tumors. The operative time was 333 min, and blood loss was 1335 mL. Pathological examination of the cervix and vaginal wall demonstrated spindleshaped tumor cells showing intracytoplasmic melanin and strong reactivity for melan-A....