A Case of Sevoflurane Use during Pregnancy in the Management
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Status asthmaticus is a severe asthma exacerbation that is refractory to bronchodilator and corticosteroid treatment. Standard treatment often employed includes nebulized bronchodilators, magnesium, corticosteroids, and mechanical ventilation. Additional considerations, although rarely used, include sedatives, neuromuscular blockade, or inhaled anesthetics. Case reports of sevoflurane use in emergency departments and the pediatric population exist for the treatment of status asthmaticus prior to extracorporeal membrane oxygenation (ECMO). However, data regarding the use during pregnancy is limited. Matters are further complicated by the potential of hepatotoxicity with use of halogenated inhaled anesthetics. With informed patient consent, we present a case of refractory status asthmaticus during pregnancy with resultant hepatotoxicity....

https://www.hindawi.com/journals/criog/2017/3547242/
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