A Scientist Poisoned Himself to Find a Cure for Stomach Ulce
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In the early 1980s, the majority of scientists thought that stomach ulcers were caused by stress or poor diet. But a handful of scientists had a different theory: They believed that ulcers were caused by a corkscrew-shaped bacterium called Helicobacter pylori.

Robin Warren, a pathologist, and Barry Marshall, an internist, were the two pioneers of this theory, and the two teamed up to study H. pylori at the Royal Perth Hospital in 1981.

They couldn't readily test their theory, since the pair only had lab mice at their disposal and H. pylori infect only humans and non-human primates, such as rhesus monkeys.

So Marshall took an unconventional approach. First, he underwent two tests to get a baseline reading of his stomach, which showed no presence of H. pylori.

Then, Marshall took some H. pylori bacteria from a petri dish, mixed it with beef extract to create a broth, and gulped it down.

If his theory was correct, a second gastric biopsy would show that his stomach was overrun with H. pylori bacteria, and a second endoscopy would show a painfully inflamed stomach – gastritis.

Less than a week later, Marshall started feeling sick. And then he started on a regimen of antibiotics to kill off the burgeoning bacteria, so a follow-up biopsy showed no signs of H. pylori.

A follow-up endoscopy, however, showed “severe active gastritis” along with epithelial damage. This was the smoking gun other clinicians needed to believe that H. pylori caused gastritis and stomach cancer.

Today, antibiotics are the standard of care for anyone afflicted with gastritis.

In 2005, Marshall and Warren were awarded the Nobel Prize in Physiology or Medicine for their discovery of H. Pylori and its role in developing gastritis and peptic ulcers.

Source: https://leapsmag.com/he-poisoned-himself-to-find-a-cure-for-stomach-ulcers-and-won-a-nobel-prize/
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G●●●l K●●●h General Medicine
Researchers, be like Dr.Marshall..
Jul 29, 2020Like3