A Successful Mother and Neonate Outcome for a Woman with Ess
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Essential thrombocytosis (ET) is a myeloproliferative neoplasm characterized by thrombocytosis which is at high risk for thrombotic events. Two-thirds of the patients harbor the JAK2V617F mutation. Conversely, FV Leiden is a common and mild form of hereditary thrombophilia. An uncommon case of coexistence of ET and FV Leiden heterozygosity in a 36-year-old pregnant woman and her successful pregnancy outcome is described. She was considered to be at high risk of thrombosis during her pregnancy and she was treated with both prophylactic dose of LMWH and aspirin daily throughout her pregnancy and for a 6-week period postpartum. The efficacy of the anticoagulation treatment was monitored in various time points not only by measuring anti-Xa levels and D-Dimers but also with new coagulation methods such as rotation thromboelastometry and multiplate....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830723/
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