A case report of successful physiological pacing in a patien
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A 52-year-old gentleman with a family history of cardiomyopathy, presented with asymptomatic atrial fibrillation and complete atrio-ventricular (AV) block associated with a narrow QRS interval. Investigations confirmed dilated and severely impaired left ventricular systolic function. He underwent successful conduction system pacing in combination with a primary prevention defibrillator. Genetic screening confirmed LMNA cardiomyopathy. During 3-years follow-up, his left ventricular function remained unchanged with stable conduction system capture and he received appropriate therapy from his device for ventricular tachycardia. His-bundle pacing promotes rapid and synchronous activation of the ventricles via the hearts intrinsic conduction system. In selected individuals with LMNA cardiomyopathy, conduction system pacing is viable alternative to conventional cardiac resynchronisation therapy using coronary sinus tributaries.

Source: https://academic.oup.com/ehjcr/advance-article/doi/10.1093/ehjcr/ytac324/6653168?rss=1