A late onset of choroidal metastasis from renal cell carcino
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Renal cell carcinoma (RCC) accounts for 2% to 3% of all adult malignancies and shows a high potential for metastatic disease. Occurrence of distant metastasis appears in approximately one-third of cases after nephrectomy. The most common sites of spread are the lungs, bones, and liver. Metastasis of RCC into choroid is highly uncommon. In a retrospective review of 420 patients with uveal metastasis, performed by Shields et al, primary RCC was found in only 2% of cases. We report a rare presentation of choroidal metastasis occurring 25 years after the resection of RCC. To our knowledge, this is the longest reported interval between initial presentation of a primary malignancy and development of ocular metastasis.

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