A neonate with subcutaneous fat necrosis after passive cooli
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Subcutaneous fat necrosis (SCFN) of the newborn is a condition characterized by inflammation of subcutaneous fat tissue in term and postterm neonates. The best recognized risk factors for the development of SCFN are asphyxia and hypothermia. The hypoxic conditions created by cold and hypoperfusion trigger the development of granulomatous inflammation of subcutaneous fat tissue followed by necrosis. Other predisposing factors include maternal diabetes, preeclampsia, cocaine abuse or use of calcium channel blockers during pregnancy, birth asphyxia, meconium aspiration, hypothermia, hypoxemia and hypoglycemia. Presented here is a case of a newborn who required mechanical ventilation immediately after birth due to respiratory failure thought to have developed as a result of meconium aspiration. With a suspicion of birth asphyxia, passive cooling was performed after which SCFN developed 3 days postnatally....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722966/
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