A non-pregnant woman with elevated beta-HCG: A case of para-
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There is a broad range of possible diagnoses for an elevated beta human chorionic gonadotropin (?-hCG) in the absence of intrauterine or ectopic pregnancy. When women of child bearing potential undergo evaluation for clinical trial, it is often unclear what course of evaluation to take when a pregnancy test is positive. We describe the clinical course of a patient with widely metastatic mucinous ovarian carcinoma with metastasis to the peritoneum, lymph nodes and liver. The patient was found to have a mildly elevated ?-hCG during initial evaluation for clinical trial. Extensive work up for ectopic pregnancy, trophoblastic disease, and phantom ?-hCG were negative. The patient's ?-hCG levels continued to rise until initiation of therapy. She was treated on a phase I protocol with restaging scans revealing a partial response. The ?-hCG was retested and declined in conjunction with her response, consistent with paraneoplastic ?-hCG....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910296/
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