A novel cause of fungal keratitis: C.dubliniensis
The present case has been reported in the journal ID cases. A 45-year-old female with history of contact lens wear presented with a persistent corneal ulcer that was unresponsive to topical moxifloxacin. The patient’s exam was concerning for fungal keratitis.

Cultures were obtained, and the patient was started on fortified amphotericin B drops and oral voriconazole. The cultures identified Candida dubliniensis as the causative organism. The patient’s exam worsened despite treatment, and the decision was made for surgery.

At the time of surgery, her cornea was found to have unexpectedly perforated. She underwent cryotherapy; tectonic penetrating keratoplasty; anterior chamber tap; intracameral voriconazole, amphotericin B, and cefuroxime; and a partial conjunctival flap. Pathology from the cornea showed GMS and PAS stains positive for fungal forms.

Key takeaway:-
C. dubliniensis is a novel cause of fungal keratitis that can be difficult to identify and treat but is fortunately likely less virulent than C. albicans and generally susceptible to available anti-fungal therapies.

Read in detail here: https://pxmd.co/0ALsa
D●●●●●●●a H●●●●i
D●●●●●●●a H●●●●i General Medicine
Jan 14, 2019Like