A single hormone directs body's responses to low-protein die
A new study from Pennington Biomedical Research Center, found that reducing the amount of protein in the diet produced an array of favorable health outcomes, including an extension of lifespan, and that these effects depend on a liver-derived metabolic hormone called Fibroblast Growth Factor 21 (FGF21).

A single hormone appears to coordinate the lifespan extension produced by a low-protein diet. Low-protein diets produce beneficial metabolic effects in aged mice, improving metabolic health, reducing frailty, and extending lifespan. These beneficial effects were also apparent when protein intake was reduced in middle-aged mice, even protecting against the detriments of obesity. Importantly, these beneficial effects were lost in mice that lacked FGF21, suggesting that its action in the brain is critical for the increase in health and lifespan.

Source:https://www.sciencedaily.com/releases/2022/05/220513103509.htm
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