A type of 'step therapy' is an effective strategy for diabet
A specific step strategy, in which patients with diabetic macular edema start with a less expensive medicine and switch to a more expensive medicine if the vision does not improve sufficiently, gives results similar to starting off with the higher-priced drug. The main complication of diabetic macular edema, fluid build-up in the retina that causes vision loss, is commonly treated with anti-vascular endothelial growth factor (VEGF) drugs. The study showed that switching treatments when needed is a reasonable strategy.

Source: https://www.nejm.org/doi/10.1056/NEJMoa2204225