A year since the pandemic: What COVID-19 treatments work, do
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Get authentic, real-time news that helps you fight COVID-19 better.
Install PlexusMD App for doctors. It's free.
Nearly a year after mysterious pneumonia emerged in China and began its global spread, there is still no silver bullet treatment for COVID-19 despite an unprecedented effort to discover new medicines or repurpose existing drugs.

A single-family of cheap, widely available medications — corticosteroids — has proven its effectiveness, but some other drugs that were initially hyped have disappointed.

What works?

Dexamethasone: Only treatment that has reduced mortality from COVID-19, shown to work for severely ill hospitalized patients and needing oxygen therapy.

Anticoagulants: Like corticosteroids, these drugs are used only in the most severely ill patients. The goal is to prevent blood clots, one of the serious complications of COVID-19.

What doesn't work well enough?

Remdesivir: For a time this antiviral treatment had the hopes of the world riding on it. But, on November 20, WHO said remdesivir should not be used to treat COVID-19 patients no matter how serious their illness, saying it had "no important effect" on survival chances.

What does not work at all?

Hydroxychloroquine: Study after study has shown that it is not effective against COVID-19 including the British trial Recovery, whose results were published in the New England Journal of Medicine in October.

Lopinavir-ritonavir: Used against HIV, the virus that causes AIDS, this one-two antiviral punch has shown to be ineffective at treating COVID-19 in hospital settings, according to the Recovery trial, which published its results in The Lancet in October.

Still under investigation

Tocilizumab: Scientists hope this immunosuppressant, currently used against rheumatoid arthritis, will be able to prevent potentially deadly inflammation in serious cases.

Synthetic antibodies: Synthetic Antibodies treatment manufactured by Eli Lilly, have received authorization for emergency use in the US. But their effectiveness continues to be evaluated, with the Regeneron treatment included in the Recovery trial.

Plasma: Recovery has an ongoing clinical trial for plasma treatment.

Source: https://www.firstpost.com/health/a-year-since-the-pandemic-what-covid-19-treatments-work-dont-work-and-were-big-disappointments-9057571.html
D●●●●●●a S●●●h and 9 others like this12 shares
Dr. L●●l S●●●●●a
Dr. L●●l S●●●●●a General Medicine
It is expected to be worthwhile but it seems that the evaluation is to use Remidahavar is yet to be decided by science for its use
Nov 28, 2020Like2