ADHD at Age 7 and Functional Impairments at Age 10
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Attention-deficit/hyperactivity disorder (ADHD) cohort studies have typically involved clinical samples and have usually recruited children across wide age ranges, limiting generalizability across complexity and developmental stage. Researchers compared academic, emotional-behavioral and social functioning at age 10, and predictors of outcomes, in a nonreferred cohort of children recruited at age 7, between those with full-syndrome (FS) ADHD and controls with no ADHD.

This was a prospective cohort study with a 3-year follow-up period. Children were recruited from 43 socioeconomically diverse schools in Melbourne, Australia. Multi-informant outcomes at age 10 were academic functioning (Wide Range Achievement Test 4; Social Skills Improvement System), emotional-behavioral functioning (Strengths and Difficulties Questionnaire total), and social functioning (Strengths and Difficulties Questionnaire peer problems). Outcomes were compared across the groups by using adjusted random-effects linear regression analyses.

Results:
-- In total, 477 children (62% male) were recruited at a mean (SD) age of 7.3 years.

-- There were 179 participants with FS ADHD, 86 with ST ADHD, and 212 controls.

-- Sample retention was 78.2% at 3-year follow-up. Both the FS and ST groups were functioning worse than controls on almost all outcome measures.

-- The best predictors of outcome for children with ADHD were working memory, ADHD symptom severity and autism spectrum disorder symptoms.

Conclusively, Children with FS and ST ADHD at age 7 experience persisting functional impairments across domains at age 10. The predictors identified at age 7 present potential targets for intervention to ameliorate impairments.

Source: https://pediatrics.aappublications.org/content/early/2020/10/03/peds.2020-1061
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