Acute Respiratory Failure in a Patient Presenting T-cell Pro
Case Report

A 36-year-old male patient was admitted in intensive care unit (ICU) for acute respiratory failure. He was diagnosed five months before referral with T-cell prolymphocytic leukemia, with massive splenomegaly and hepatomegaly, characterized by bloodstream and bone marrow involvement by mature T-cells harboring CD3+/dim, CD8+, CD4-, CD5+ and CD7+ phenotype. He was initially treated with the purine analog pentostatin. He relapsed after two courses, four weeks before respiratory symptoms onset. On admission in ICU, respiratory rate was 36 cycles mn-1, body temperature was 38.1°C, arterial pressure was 116/79 mmHg, heart rate was 128 mn-1...

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http://www.omicsonline.org/open-access/acute-respiratory-failure-in-a-patient-presenting-tcell-prolymphocyticleukemia-specific-leukemic-lung-involvement-2472-1247-1000116.php?aid=75091
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