Acute lymphoblastic leukemia with pancreas involvement in an
Acute lymphoblastic leukemia (ALL) is a malignant disease originating from abnormal proliferation of B or T lymphocytes in bone marrow (BM). Invasion of the pancreas is extremely rare in adults.

In this article, Medicine: June 2019 - Volume 98 - Issue 23 - p e15685 reports a case presenting that ALL invades the pancreas, as well as liver, kidney, and duodenum detected by magnetic resonance image. The patient was misdiagnosed as pancreatic tumor at initial since hemogram was unremarkable. The diagnosis of ALL was established based on the endoscopic ultrasonography-guided fine-needle aspiration and bone marrow examination, showing BCR/ABL gene positive.

The patient was actively treated with chemotherapy. Hematological remission was obtained and the lesions in the pancreas disappeared. The patient finally died of complication from fungal pneumonia and central nervous system involvement 12 months after diagnosis.

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Is it possible to have ALL in adults with BCR ABL gene positive????
Jun 30, 2019Like