Adaptive Radiotherapy for an Uncommon Chloroma
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Granulocytic sarcomas, also referred to as chloromas or myeloid sarcomas, are extramedullary neoplasms that are composed of immature myeloid cells. This uncommon disease is known to be radiosensitive. However, the total dose and dose per fraction are not standardized. In addition, during the course of radiation therapy, significant reduction of the tumor is usually obtained. Thus, target volume reduction may require an intermediate radiotherapy plan evaluation for an adaptive treatment. A second plan at mid-dose is highly recommended. We report a 60-year-old white man with a history of AML in the first complete remission after allergenic stem cell transplantation. Four years later, he developed a mass of soft tissues in the lower third of the posterior compartment of his left thigh, gradually increasing, as well as stiffness of the left knee.....

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