Allergies may be risk factors for cardiovascular diseases
Researchers examined results from preclinical models and lab-based studies, which point to specific types of inflammatory cells that may accumulate in the lungs, heart, and vasculature, helping orchestrate asthma and CVD.

Both clinical and pre-clinical studies pointed to shared mechanisms for CVD and asthma. The authors looked at how asthma medications that act on some of these mechanisms might influence risk of CVD. They found that:
-Inhaled albuterol (commonly used as "rescue inhalers" to treat acute asthma attacks) seemed to reduce CVD risk.
-Oral and intravenous corticosteroids (such as prednisone) appeared to increase CVD risk, but inhaled corticosteroids (such as fluticasone propionate and budesonide) appeared to decrease CVD risk.
-Leukotriene modifiers (such as montelukast) had beneficial effects, reducing inflammation, blood lipid levels and cardiovascular events.
-Anti-asthma antibodies (such as omalizumab) had mixed results, with one study finding increased risk and others showing reduced risk or no effect on CVD.
-Mast cells are among the common white blood cells that are activated by circulating IgE in patients with asthma or allergies.

Source: https://www.nature.com/articles/s44161-022-00067-z
Like
Comment
Share