Allogeneic bone application in association with platelet-rich plasma is helpful in reducing the need for additional donor sites and also decreases the timing of hospital stay for alveolar bone grafting of cleft palate defects.
The aim of this study is to compare allogeneic bone grafts associated with platelet-rich plasma (ALBGs-PRP) to autogenous bone grafts (ATBGs) for alveolar reconstructions in patients with cleft lip and palate (CLP).
Thirty out of 46 patients with 8–12 years of age and pre-or trans-foramen unilateral clefts were operated by the same surgeon. Groups were selected randomly after coin-toss for the first surgery to be ALBG-PRP. Pre- and post-surgery cleft defect severity was registered by a scoring system using superimposed digitalized peri-apical radiographs. The hypothesis indicated ABG-PRP to be similar to the ABG was proved.
There was no statistically significant difference in bone augmentation for the ABG-PRP group when compared to the ABG group.
Conclusively, ABG-PRP is indicated as a successful treatment modality to reduce the need for additional donor sites and reduce morbidity and hospital stay.
Contemporary Clinical Dentistry