Ambient particulate matter air pollution is associated with
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A higher concentration of fine particulate matter in air pollution is significantly linked with the incidence of papillary thyroid carcinoma with the exposure of 2 and 3 years. The study was published in Surgery.

Researchers sought to estimate the relationship between long-term exposure to the fine (diameter <2.5 ?m) particulate matter component of air pollution and the risk of papillary thyroid cancer.

Adult patients with newly diagnosed papillary thyroid carcinoma across a single health system were identified using electronic medical records. Data from 1,990 patients with papillary thyroid carcinoma were compared with 3,980 age- and sex-matched control subjects without any evidence of thyroid disease. Cumulative fine (diameter <2.5 ?m) particulate matter exposure was estimated by incorporating patients’ residential zip codes into a deep learning neural networks model, which uses both meteorological and satellite-based measurements.

- Increased odds of developing papillary thyroid carcinoma were associated with a 5 ?g/m3 increase of fine (diameter <2.5 ?m) particulate matter concentrations over 2 years and 3 years of exposure.

- This risk differed by smoking status. Among current smokers, the risk of developing papillary thyroid carcinoma was highest.

Conclusively, the increasing concentration of fine (diameter <2.5 ?m) particulate matter in air pollution is significantly associated with the incidence of papillary thyroid carcinoma with 2 and 3 years of exposure.

Source: https://doi.org/10.1016/j.surg.2021.05.002
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