Ameloblastic carcinoma of the maxilla: A rare case
Ameloblastic carcinoma (AC) is an uncommon malignant tumor with aggressive behavior which accounts for less than 4% of odontogenic tumors. The following case has been reported in the Journal of Solid Tumors.

A 40-year-old male was referred with a complaint of a painful and rapid growing mass in the right posterior maxilla which was noticed 3 months earlier. Intra-oral examination revealed the expansion of the posterior right maxilla, increasing hard palate volume, intact mucosa covering, and firm consistency. No previous medical history or trauma was detected.
Ameloblastic carcinoma (AC) is an uncommon malignant
tumor with aggressive behavior which accounts for less than
4% of odontogenic tumors.

Panoramic radiograph revealed an ill-defined unilocular ra-diolucent lesion in the posterior area of the maxilla. On the basis of clinical and imaging findings, a provisional diagnosis of malignant tumor arising from the maxillary bone was made. An incisional biopsy was done and was submitted to oral and maxillofacial pathology service.

Microscopically, the sections showed a malignant odontogenic tumor composed of cords, sheets and islands consistent with an ameloblastic lesion. Peripheral palisading of columnar cells, reverse polarized nuclei and stellater eticulum structure were observed in the tumoral islands. However, evidence of nuclear hyperchromatism, pleomorphism, increased nucleus to cytoplasm ratio and mitotic activity in some areas were found.
These findings suggested a diagnosis of AC.

The patient underwent surgical procedure and hemi-maxillectomy was performed. The patient was followed up every two months. After more than a year of follow-up, no evidence of recurrence was observed.

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