An occult urothelial carcinoma with wide multiorgan metastas
Medicine: April 2019 - Volume 98 - Issue 16 - p e15245 presented an unusual case of occult urothelial carcinoma primarily manifested as a multiorgan metastatic cancer in a 59-year-old man. The patient complained of pain on the left thigh root for a month. The imaging and histopathological examination revealed multiple malignancies in lung, bone, and liver.

Based on the mutation of STK11 M51Ifs*106 detected by next generation sequencing (NGS), we started targeted therapy with everolimus. The patient deteriorated after 3 months of treatment and passed away.

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