An unusual local invasion of synovial sarcoma
A 55-year-old female with a large mass was admitted to our hospital. She had no traumatic episode. Magnetic resonance imaging (MRI) revealed a well-defined and gadolinium-enhanced mass (5.5 × 4.9 cm) in her right thigh. MRI also revealed a mass extending into the vastus intermedius muscle beyond the intermuscular septum. A needle biopsy from the mass confirmed the histological diagnosis of synovial sarcoma which was positive for SS-18 break apart by fluorescence in situ hybridization (FISH). After 2 cycles of neo-adjuvant chemotherapy, a wide resection of the tumor was performed. A histopathological examination (red square in Fig. 1) showed that the tumor had direct invasion into the intermuscular septum. Five months after the surgery, the patient has shown no sign of recurrence.

Source: Oxford Medical Case Reports, Volume 2019, Issue 4, April 2019, omz024

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