Anogenital lichen sclerosus: Change of tissue position as pa
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Lichen sclerosus (LS) is a chronic inflammatory skin disease which preferably inflicts the anogenital area.Clinically, affected skin areas exhibit pallor, atrophy, wrinkles, erosions or fissures, sclerosis and scarring, ultimately destroying skin texture, tissue compliance and normal architecture of the vulva. The pathogenesis of LS is incompletely understood, however, increasing evidence points to an autoimmune disorder involving both T-cell mediated and humoral mechanisms .We here provide a unique demonstration of LS recurrence in a pudendal thigh flap, illustrating the importance of tissue position in the pathogenesis of LS.....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357701/
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