Anomalous origin of the left coronary artery from the right
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Anomalous aortic origin of the left coronary artery (AAOLCA) from the right aortic sinus is a rare congenital anomaly associated with significantly increased risk of myocardial ischemia, arrhythmias and sudden cardiac death. This refers specifically to AAOLCA associated with intraarterial and/or intramural course. Much less is known about the anomalous origin of the left coronary artery from the right aortic sinus associated with a subpulmonic intramyocardial course.

Here reported case of a 12-year-old girl who complained of recurrent episodes of chest pain lasting for some minutes and not associated to exercise. Echocardiography revealed AAOLCA from the right aortic sinus taking a subpulmonic course within the conal septum. The diagnosis was confirmed by CT-scan and selective coronary angiography. Treadmill test, Holter-ECG and bicycle-stress echocardiography revealed no evidence of myocardial ischemia reflecting unimpaired diastolic flow in the left coronary artery. According to the nature of the complaints and in the absence of signs of myocardial ischemia the episodes of chest pain were classified as idiopathic and not associated with the coronary anomaly. The author opted for a conservative approach with regular follow-up visits. During a follow-up of 2 years without the restriction of sports activities the patient has been asymptomatic.

According to the literature AAOLCA with subpulmonary intramyocardial course appears to be associated with significantly fewer clinical problems than AAOLCA taking an intraarterial course. The diagnosis can be suspected based on echocardiography and confirmed by contrast-enhanced computed tomography. Until now there are only a few data concerning the natural history and incidence of complications in this specific anomaly. Despite the probably benign nature we recommend regular follow-up examinations including stress-testing in these patients.