Antibacterial Properties of Aloe vera on Intracanal Medicame
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Aloe vera can inhibit the growth of E. faecalis equal with common antimicrobial agents, finds a new study published in the International Journal of Dentistry.

The use of herbal compounds as an intracanal medicament in the field of endodontics has become noteworthy, one of which is the Aloe vera compound whose antibacterial effect has already been proven in the planktonic form of Enterococcus faecalis. The purpose of this study is to evaluate the antibacterial effect of Aloe vera on E. faecalis biofilms at the 4th and 6th week of development.

Despite the application of various canal cleaning techniques and tools, as well as washing solutions and antimicrobial drugs, resistant microorganisms such as Enterococcus faecalis are still a challenge to the success of root canal therapy. This bacterium is the most common microorganism in the pathogenicity of recurrent infections and resistant endemic infections, which is found in 22–77% of failed cases.

The authors used 130 single root canal teeth without anomalies and caries. They were divided into 2 groups of 65 teeth for four and six weeks of biofilm production. Study groups were investigated with an antimicrobial agent as an intracanal medicament including 20 samples treated with Aloe vera, calcium hydroxide, and phosphate-buffered saline and biofilm and survival of pathogens were investigated. Dentin chip suspensions were used for the colony-forming unit (CFU) counting to estimate the remaining E.faecalis count.

The results of the study showed that the CFU mean in the 4th-week subgroup and 6th-week subgroup in Aloe vera, phosphate-buffered saline, and calcium hydroxide was least with aloe vera and highest with phosphate-buffered saline.

Aloe vera, in contrast to calcium hydroxide, eliminated 4th and 6th week biofilms and showed remarkable antibacterial properties against E. faecalis biofilm. These results support the potency of Aloe vera to use as a natural antimicrobial material in the intracanal medicament, the authors concluded.