Aorta coarctation and systemic lupus erythematosus
Vasculitis is one of the common pathological hallmarks of systemic lupus erythematosus (SLE). Vascular lesions in SLE commonly involve medium- and small-sized vessels. Rarely, vasculitis in SLE may involve large vessels such as the aorta leading to life-threatening complications. Reported cases of large vessel lesions in SLE included aortic aneurysm and aortic dissection.

A 52-year-old Chinese woman with SLE, who was stable on oral glucocorticoid, but showed sudden intractable hypertension and heavy proteinuria before we found aorta coarctation in her computed tomography (CT) scan of the aorta. This patient's large vascular lesions were likely secondary and not a primary manifestation of lupus activity.

After endovascular stent graft repair of the abdominal aorta, her hypertension and proteinuria were controlled.

Source: Medicine: July 2019 - Volume 98 - Issue 28 - p e16397

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