Apocrine Adenocarcinoma of the Vulva
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Primary vulvar cancer constitutes less than 5% of female genital tract malignancies, and most cases are squamous cell carcinoma. Primary vulvar adenocarcinomas are very rare. Based on histopathologic criteria, they are classified into sweat gland carcinomas, primary mammary-like adenocarcinomas, and extramammary Paget's disease (EMPD). However, because of their rarity, there is no consensus on their histogenesis, prognosis or treatment strategies. In this report, we describe the rare case of primary vulvar apocrine adenocarcinoma, a histologic subtype of vulvar sweat gland carcinoma and investigate its histogenesis and molecular epidemiology with a literature review...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030426/
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