Application of Transthoracic Shear Wave Elastography in eval
The utilization of transthoracic shear wave elastography is feasible in the differentiation of subpleural masses, finds a study published in the European Journal of Radiology.

82 consecutive patients with radiographic evidence (including chest X-ray and thoracic computed tomography CT) of single subpleural lesion enrolled in this research.

The Young’s modulus E (including Emean and Emax) of each lesion was detected, and Young’s modulus E of malignant lesions was compared with those of benign ones. They made diagnoses according to the results of pathology or standard clinical course for at least 3 months. Receiver operating characteristic (ROC) analysis was plotted to determine the cut-off point by maximizing the Youden index.

- The Emean and Emax of the benign and malignant group was 34.68 ± 12.12 kPa vs. 53.82 ± 11.95 kPa, 57.77 ± 14.45 kPa vs. 76.62 ± 17.04 kPa.

- The ROC of Emean showed that when the cut-off point was 43.8 kPa, the Youden index for distinguishing benign and malignant tumors was the largest.

- When the cut-off point recommended by Emax ROC was 73.5 kPa, the Youden index for distinguishing benign and malignant tumors was the largest.

This study demonstrated that we can employ transthoracic shear wave elastography as a valuable instrument in differentiating benign subpleural lesions from malign ones.

Source: https://doi.org/10.1016/j.ejro.2021.100364
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