Assessment of Chronic bronchitis and risk factors in young A
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Chronic bronchitis is associated with substantial morbidity among elderly adults, but little is known about its prevalence and risk factors in young adults. The aim of the study was to assess the prevalence and early-life risk factors for chronic bronchitis in young adults.

Researchers assessed chronic bronchitis (CB) as the combination of cough and mucus production in the morning during winter. Environmental and clinical data from birth and onwards were used for analysis of risk factors.

Results:
--At the 24-year follow-up, 75% (n=3064) participants completed the questionnaire and 2030 performed spirometry.

--The overall prevalence of CB was 5.5% (n=158) with similar estimates in males and females. 49% of CB cases experienced more than three self-reported respiratory infections in the past year compared to 18% in non-CB subjects 1), and 37% of cases were current smokers (versus 19% of non-CB cases).

--Statistically significant lower post-bronchodilator forced expiratory volume in 1 s/forced vital capacity were observed in CB compared to non-CB subjects (mean z-score -0.06 versus 0.13).

--Daily smoking (adjusted (a)OR 3.85), air pollution exposure (black carbon at ages 1–4 years aOR 1.71 per 1microg·m 3 increase) and exclusive breastfeeding for less than 4 months (aOR 0.66) were associated with CB.

Conclusively, Recurrent respiratory infections are linked to chronic bronchitis in young adults. Aside from smoking, these findings support the importance of early-life exposures to respiratory health later in life, such as air pollution and exclusive breastfeeding.

Source: https://erj.ersjournals.com/content/57/3/2002120
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