Patient‐reported outcomes (PROs) are widely used in rheumatoid arthritis (RA) to assess different aspects of the disease, including physical function, global disease activity, pain and health‐related quality of life. An association between radiographic bone erosion and joint space narrowing (JSN) and patient‐reported physical function, as well as workability in established RA, has been reported. A study was conducted to investigate whether magnetic resonance imaging (MRI) pathologies in the wrist/hand of rheumatoid arthritis (RA) patients are associated with patient‐reported outcomes (PROs) at clinical remission and relapse.
Magnetic resonance imaging‐assessed damage was associated with impaired HAQ and SF‐36 PCS at remission and relapse, independent of clinical and radiographic measures, and was also associated with most of the hand‐related HAQ items. In multivariate models including MRI, SvH scores were not associated with PROs. MRI‐assessed inflammation was not associated with PROs at remission or relapse.
In conclusion, Magnetic resonance imaging‐assessed wrist/hand damage, but not inflammation, in patients with established RA is associated with patient‐reported physical impairment at remission and relapse. The amount of damage in the wrist/hand is associated with reduced hand function.