Association between gestational weight gain in women with ge
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The study shows the association between gestational weight gain (GWG) in women with gestational diabetes mellitus (GDM) and adverse pregnancy outcomes (APOs).

This retrospective cohort study enrolled women with GDM. Total GWG, rates of GWG in the second trimester and third trimesters were stratified into three categories according to IOM guidelines: within, below, and above IOM guidelines. Overall, 1606 women with GDM fulfilled inclusion criteria.

- Total GWG above IOM guidelines in pregnancy was associated with an increased odds of cesarean delivery, hypertensive disorders of pregnancy (HDP), preeclampsia, macrosomia, and large for gestational age (LGA), and a decreased odds of premature rupture of membrane (PROM) and preterm birth; total GWG below IOM guidelines in pregnancy was associated with an increased risk of preterm birth, small for gestational age (SGA) and a decreased odds of macrosomia and LGA.

- Further, in both second and third trimesters of pregnancy, rates of GWG above IOM guidelines were found to be associated with a high odds of HDP, preeclampsia, macrosomia, and LGA.

- Rates of GWG above IOM guidelines in the third trimester of pregnancy also increased odds of cesarean delivery when compared with within IOM guidelines.

- While rates of GWG below IOM guidelines in both second and third trimesters of pregnancy were associated with a decreased odds of macrosomia and LGA. In addition, the rate of GWG below IOM guidelines in the third trimester of pregnancy was associated with an increased odds of preterm birth.

Conclusively, GWG, outside IOM guidelines has increased risks of APOs among women with GDM, implying that careful surveillance for GWG during different stages of pregnancy is warranted.

BMC Pregnancy and Childbirth
Source: https://doi.org/10.1186/s12884-021-03982-4
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