Association of ABO and Rh Blood Groups with obstetric outcom
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According to a recent study, among pregnant women with SARS-CoV-2, blood groups A and Rh+ are associated with medical and obstetric morbidity.

The objective was to evaluate the influence of ABO and Rh blood groups on morbidity among SARS-CoV-2 infected pregnancies.

Pregnant women with SARS-CoV-2 tested with polymerase-chain-reaction were included. A cohort of 1,278 SARS-CoV-2(+) pregnant women were analyzed and a concurrent comparison group of 1,453 SARS-COV-2(-) patients was established.

- Differences were noted between blood types and Rh for age and ethnicity comparing SARS-CoV-2(+) and SARS-CoV-2(-) groups.

- Among the SARS-CoV-2(+) cohort, the odds of symptomatic COVID-19 and obstetric hemorrhagic event were higher in Rh+ vs Rh- mothers, and preterm premature rupture of membranes (PPROM) were higher among blood type A vs non-A mothers.

In SARS-CoV-2(+) pregnant women, Rh- status was associated with a lower risk of symptomatic COVID-19, while Rh+ and blood group A was associated with obstetric hemorrhage and PPROM, respectively.

European Journal of Obstetrics & Gynecology and Reproductive Biology
Source: https://doi.org/10.1016/j.ejogrb.2021.07.008
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