Association of Cannabis Vaping with Respiratory Symptoms in
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The purpose of this study was to explore the association between respiratory symptoms among U.S. adolescents who were current (past 30-day) users of cigarettes, e-cigarettes, and/or cannabis, as well as lifetime users of cannabis with electronic nicotine delivery systems (ENDS).

Wave 4 from a national probability sample (N = 14,798) of adolescents (12–17 years) using Population Assessment of Tobacco and Health Study data was used for this study. Retention rate was 88.4%.

Results:
--The odds of indicating “wheezing or whistling” in the chest were roughly two times higher among those who had used cannabis in ENDS (adjusted odds ratio 1.81);
--Neither e-cigarettes nor cigarettes had a significant association with all five respiratory symptoms in the fully adjusted models.

Finally, this report offers tentative evidence that teenage cannabis use associated with ENDS can have negative health implications. With ENDS, long-term cannabis use was significantly linked to an increased risk of respiratory symptoms.

Source: https://www.jahonline.org/article/S1054-139X(21)00047-1/fulltext
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