Association of Pilonidal Disease with Polycystic Ovarian Syn
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This study states that in patients having Pilonidal Disease (PD) the chances of occurrence of Polycystic Ovarian Syndrome (PCOS) is increased. Pilonidal disease and PCOS are associated with significant morbidity and decreased quality of life, thus early diagnosis and treatment are important.

In the study published by the Journal of Pediatric and Adolescent Gynecology, the researchers sought to determine whether the pilonidal disease is associated with PCOS and whether the severity of PD is greater in patients with concurrent PCOS and whether treatment of PCOS reduces pilonidal disease severity.

Inclusion criteria were all girls aged 12 to 21 receiving a diagnosis of PCOS or PD from 2012-2019 at a tertiary medical center. Variables analyzed included age, race/ethnicity, BMI, menarche, tobacco use, payer status, treatment of PCOS and PD, serum markers of hyperandrogenism, and metabolic syndrome. Data were analyzed with Student's t-test, chi-squared test, and multiple logistic regression.

In total, 100043 patients presented to an urban tertiary medical center with 769 patients diagnosed with PD of which 209 patients were diagnosed with both PD and PCOS.

--Patients with both diagnoses were more likely to have a higher BMI, and be older.

--The odds of patients with PD having PCOS was 34.6 times that of patients without PD.

--Patients with both diagnoses were less likely to receive intervention for PD.

Overall, there is a higher prevalence of PCOS among adolescent girls diagnosed with PD. PCOS treatment appears to confer a protective effect in reducing the risk of intervention for PD. Increased awareness of the association between PCOS and PD among providers taking care of female adolescents with PD should result in a lower threshold for screening for PCOS and/or referral to adolescent gynecology for further evaluation.

Source: https://doi.org/10.1016/j.jpag.2021.02.095
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