Association of Salivary Statherin, Calcium, and Proline-Rich
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According to a recent study by the International Journal of Dentistry salivary components help to predict the oral hygiene status. Increased statherin and reduced acidic proline-rich proteins (aPRP) are reported in individuals with poor oral hygiene.

Saliva, as a complex biofluid, plays a pivotal role in maintaining oral health and tooth integrity. This study aims to investigate the association between salivary statherin, acidic proline-rich proteins (aPRP), and calcium with oral hygiene status.

188 healthy subjects with varying oral hygiene status who gave consent to participate were included in this cross-sectional study. Oral hygiene of all the participants was measured using Oral Hygiene Index–Simplified (OHI-S). Stimulated saliva collected using paraffin wax was analyzed for salivary statherin, aPRP, and calcium. The relationship between salivary statherin, aPRP, and calcium levels with OHI-S was assessed using Spearman’s Rank correlation coefficient; the strength of the relationship was assessed by multiple linear regression analysis.

The study found a weak positive correlation between salivary statherin and OHI-S; a weak negative correlation between salivary aPRP and OHI-S; and a moderate negative correlation between salivary statherin and salivary aPRP levels which were statistically significant.

In conclusion, poor oral hygiene is associated with increased statherin and reduced aPRP levels in saliva. Thus, these salivary components may have a role in predicting oral hygiene status.

Source: https://doi.org/10.1155/2021/1982083
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