Association of schistosomiasis and HIV infections: a review
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Female genital schistosomiasis (FGS) affects up to 56 million women in sub-Saharan Africa and may increase risk of HIV infection.

This study aimed to assess the association of schistosomiasis with HIV infection, authors examined peer-reviewed literature published until December 31, 2018 and generated a pooled estimate for the odds ratio using Bayesian random effects models.

Results:
-- Of the 364 abstracts identified, 26 were included in the summary.

-- Eight reported odds ratios of the association between schistosomiasis and HIV; one reported a transmission hazard ratio (HR) of 1·8 among women and 1·4 among men; 11 described the prevalence of schistosomiasis among HIV-positive persons; and six reported the prevalence of HIV among persons with schistosomiasis.

-- Six studies were selected for quantitative analysis. The pooled estimate for the odds ratio of HIV among persons with schistosomiasis was 2·3.

Conclusively, researchers found a significant association of schistosomiasis with HIV. However, we could not generate a specific summary estimate for FGS. This provides a research agenda to determine the effect of FGS on HIV infection. WHO’s policy on mass drug administration for schistosomiasis may prevent HIV.

Source: https://www.ijidonline.com/article/S1201-9712(20)32292-X/fulltext?rss=yes
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