Autologous blood clot covering instead of gas tamponade for
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This study evaluates the efficacy and usefulness of vitrectomy with internal limiting membrane peeling and autologous blood clot covering without gas tamponade in the treatment of macular holes (MHs). All patients with a full-thickness MH with a minimum diameter of less than 600 µm and a base diameter of less than 1,200 µm underwent pars plana vitrectomy and internal limiting membrane peeling with autologous blood covering the MH at the end of the surgery. No fluid–air exchange or gas tamponade was performed. Postoperatively, all patients were instructed to adopt supine position overnight and thereafter any comfortable posture.

A total of 18 eyes of 18 consecutive patients were included. The mean age of the patients (12 women and 6 men) range, 21–81 years. The MHs composed of 13 idiopathic MHs, 2 MHs with high myopia, 2 traumatic MHs, and 1 MH associated with diabetic macular edema. Among them were five large MHs. Complete MH closure was achieved in all eyes at the end of the follow-up period. Visual acuity was significantly improved from preoperative 0.89 ± 0.41 logarithm of the minimum angle of resolution (20/155 Snellen) to 0.42 ± 0.33 logarithm of the minimum angle of resolution (20/53 Snellen) at the final visit.

The novel surgical protocol using vitrectomy, internal limiting membrane peeling, and autologous blood clot covering at the end of the MH surgery with limited diameters achieved highly effective closure and visual improvement and eliminated the gas tamponade and thus the associated adverse effects and the need for postoperative face-down positioning.

Source:https://journals.lww.com/retinajournal/Abstract/2020/09000/AUTOLOGOUS_BLOOD_CLOT_COVERING_INSTEAD_OF_GAS.13.aspx
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