Avoid Taking Ibuprofen for COVID-19 Symptoms, says WHO
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The World Health Organization recommended that people suffering COVID-19 symptoms avoid taking ibuprofen after French officials warned that anti-inflammatory drugs could worsen the effects of the virus.

WHO spokesman Christian Lindmeier told that UN health agency's experts were "looking into this to give further guidance." "In the meantime, we recommend using rather paracetamol, and do not use ibuprofen as self-medication. That's important," he said. His comments came after Veran sent a tweet cautioning that the use of ibuprofen and similar anti-inflammatory drugs could be "an aggravating factor" in COVID-19 infections.

The French minister stressed that patients already being treated with anti-inflammatory drugs should ask for advice from their doctor. Even before the pandemic, French authorities sounded the alarm over serious "infectious complications" linked to the use of ibuprofen, which is sold under various brands like Nurofen and Advil, and other anti-inflammatory drugs.

His comments seem to have stemmed in part from remarks attributed to an infectious diseases doctor in south west France. She was reported to have cited four cases of young patients with covid-19 and no underlying health problems who went on to develop serious symptoms after using non-steroidal anti-inflammatory drugs (NSAIDs) in the early stage of their symptoms. The hospital posted a comment saying that public discussion of individual cases was inappropriate.

Experts in the UK backed this sentiment by adding, “The finding in two randomised trials that advice to use ibuprofen results in more severe illness or complications helps confirm that the association seen in observational studies is indeed likely to be causal. Advice to use paracetamol is also less likely to result in complications.”

Ian Jones, a professor of virology at the University of Reading, said that ibuprofen’s anti-inflammatory properties could “dampen down” the immune system, which could slow the recovery process. He added that it was likely, based on similarities between the new virus (SARS-CoV-2) and SARS I, that covid-19 reduces a key enzyme that part regulates the water and salt concentration in the blood and could contribute to pneumonia seen in extreme cases. “Ibuprofen aggravates this, while paracetamol does not,” he said.

There is speculation that the drug might prevent fatal “cytokine storms,” in which the immune system of seriously ill patients can cause organ failure.

Source: https://www.sciencealert.com/who-recommends-to-avoid-taking-ibuprofen-for-covid-19-symptoms


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