Bariatric Surgery Tied to Lower Death Risk in Some T2D Patie
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The JAMA Network study findings suggest that bariatric surgery was associated with substantially lower all-cause mortality as well as nonfatal diabetic events in patients with type 2 diabetes.

The aim of this study was to determine the association between bariatric surgery and all-cause mortality among patients with type 2 diabetes and severe obesity.

This retrospective, population-based matched cohort study included patients with type 2 diabetes and body mass index 35 or greater who underwent bariatric surgery. Multiple linked administrative databases were used to define confounders, including age, baseline BMI, sex, comorbidities, duration of diabetes diagnosis, health care utilization, socioeconomic status, smoking status, substance abuse, cancer screening, and psychiatric history. Potential controls were identified from a primary care electronic medical record database.

A total of 6910 patients were included, with 3455 patients who underwent bariatric surgery and 3455 match controls, and a median follow-up time of 4.6 years.

--In the surgery group, 83 patients died, compared with 178 individuals in the control group.

--Bariatric surgery was associated with a 68% lower cardiovascular mortality and a 34% lower rate of composite cardiac events.

--Risk of nonfatal renal events was also 42% lower in the surgical group compared with the control group.

--Of the groups that had the highest absolute benefit associated with bariatric surgery, men had an absolute risk reduction (ARR) of 3.7%, individuals with more than 15 years of diabetes had an ARR of 4.3%, and individuals aged 55 years or older had an ARR of 4.7%.

These findings suggest that bariatric surgery was associated with reduced all-cause mortality and diabetes-specific cardiac and renal outcomes in patients with type 2 diabetes and severe obesity.

Source: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2778938
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