Bariatric surgery is associated with lower BMD and Osteoporo
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Recent research has highlighted that despite a similar lifestyle, Bariatric surgery, Roux-en-Y gastric bypass was followed by a lower bone mineral density compared to controls. Further, the team observed that the reduced BMD in RYGBP can not be explained, seemingly nor prevented, by lifestyle factors.

Bariatric surgery, RYGBP in particular, is associated with weight loss as well as low bone mineral density. Bone mineral density relies upon multiple factors, some of which are lifestyle factors. The aim of this study was to compare lifestyle factors in order to eliminate them as culprits of the suspected difference in BMD in RYGBP operated and controls.

Study participants included 71 RYGBP-operated women and 94 controls. Each completed a DEXA scan, as well as a survey of lifestyle factors. All study participants were premenopausal Caucasian women living in the same area. Blood samples were taken in RYGBP-patients.

Results were;
--BMD was significantly lower in RYGBP, femoral neck 0.98 vs. 1.04 g/cm2 compared to controls, despite higher BMI and similar physical activity and calcium intake.

--In a multivariate analysis, increased time since surgery and age was negatively associated with BMD of the femoral neck and total hip in RYGBP patients.

In summary, despite a similar lifestyle, RYGBP was followed by a lower BMD compared to controls. Thus, the reduced BMD in RYGBP cannot be explained, seemingly nor prevented, by lifestyle factors. As the reduction in BMD was associated with time since surgery, strict follow-up is a lifelong necessity after bariatric surgery, and especially important in younger bariatric patients.

BMC Surgery
Source: https://doi.org/10.1186/s12893-021-01281-5
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