Beneficial Effects of Isoproterenol and Quinidine in the Tre
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The use of an implantable cardiac defibrillator in patients with Brugada Syndrome (BrS) has been advocated as the first line therapy for managing recalcitrant ventricular fibrillation (VF). However, this device is only useful for terminating VF. Intermittent and/or refractory VF for which lifesaving cardioversion occurs is a problematic situation in this patient population. After an initial adverse arrhythmic event, such as cardiac arrest or syncope due to VF, approximately 60% of symptomatic patients will have a recurrent arrhythmic event within the next 4 years.This case and literature review will focus on the effectiveness of isoproterenol (ISP) and quinidine in preventing VF in patients with BrS....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480801/
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