Bilateral Sertoli Cell Tumors in a Patient with Androgen Ins
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Androgen insensitivity syndrome is the most common cause of male pseudohermaphroditism and the third most common cause of primary amenorrhea. This genetic alteration is a consequence of inherited defects on the X chromosome causing total or partial damage to the intrauterine virilization process due to functional abnormalities in the androgen receptors. The clinical signs that characterize the disease consist of female behavior, complete lack or scarcity of axillary and pubic hair, adequate female breast development, female external genitalia, blind vaginal pouch, absence of internal genitalia, and the presence of gonads with seminiferous tubules; however, spermatogenesis is absent .The present report describes a 22-year-old patient with a female phenotype and a 46, XY karyotype, presenting with bilateral inguinal tumors. The tumors were surgically removed. Pathology revealed bilateral testicles with Sertoli cell tumors....

https://www.hindawi.com/journals/criog/2017/8357235/
Like
Comment
Share