Bilateral optic neuritis: A new twist on immune reconstituti
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The diagnosis and treatment of optic neuritis in HIV/AIDS are especially challenging because of the broad differentials and profound immunosuppression. The differentials can be divided into infectious and noninfectious causes and include viral infection (primarily cytomegalovirus), toxoplasmosis, tuberculosis, syphilis, Leber hereditary optic neuropathy, tumor metastasis, meningitis, multiple sclerosis, and neuromyelitis optica. A 24-year-old African American male with a history of HIV/AIDS presented to the emergency department with a 2-day history of progressive loss of vision OD and pain with eye movement. He had been diagnosed with HIV/AIDS 5 years previously. He was noncompliant with his medications because of a recent incarceration.

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