Brisk walking may slow biological aging process
A new study of genetic data of more than 400,000 UK adults has revealed a clear link between walking pace and a genetic marker of biological age. Researchers studied genetic data from 405,981 middle-aged UK Biobank participants and found that a faster walking pace, independent of the amount of physical activity, was associated with longer telomeres.

Telomeres are the "caps" at the end of each chromosome, and they hold repetitive sequences of non-coding DNA that protect the chromosome from damage, similar to the way the cap at the end of a shoelace stops it from unraveling.

Each time a cell divides, these telomeres become shorter—until a point where they become so short that the cell can no longer divide, known as "replicative senescence." Therefore, scientists consider LTL a strong marker for "biological age," independent from when an individual was born. Although the relationship between telomere length and disease is not fully understood, the build-up of these senescent cells is believed to contribute to a range of symptoms we associate with aging, such as frailty and age-related diseases.

Source: https://www.nature.com/articles/s42003-022-03323-x
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